Release Notes 6.6.2

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Discngine assay, version 6.6.2

Release Date: February 6, 2026

Assay

New Features

#13818 Upgrade Spotfire Compatibility to version 14.6 LTS

  • Assay is now compatible with TIBCO Spotfire 14.6 LTS. This is the only version supported by the application.

13811 - Multiple Screen Visualization in Assay using Spotfire

A new Open in a new window button is available on the Spotfire visualization page, allowing you to open a dedicated Spotfire page in a separate window.

  • View different information on two screens to speed up your analysis
  • The marking from the main page is kept on the second page

13427 - Be able to search by compound in Assay

A new Search page is available from the Assay menu, allowing you to find runs associated with sample names or sample aliases.

  • Enter a list of sample names or aliases (one per line)
  • View all runs associated with these samples
  • Open one run or multiple runs to display them as cross runs

13747 - Median and MAD Available with Basic Stats analysis

The Basic Stats analysis now calculates the Median and MAD (Median Absolute Deviation) in addition to the existing statistics (average, standard deviation, count).

  • When computing the basic stats at the Sample Analysis Settings step, the median and MAD are automatically calculated
  • The results are visible at the Sample Analysis step and can be published

Improvements

13243 - Improve visualization pages look & feel

The visualization pages (Well Validation, Reference and Sample Analysis, Cross Runs) have been enhanced for a better user experience:

  • For the Cross Runs page, the left panel has been removed. Run invalidation is now accessible via a dedicated modal page.
  • For Well Validation, Reference and Sample Analysis pages, the look and feel of the left panel actions (Normalizations, Automatic Analysis, etc.) have been updated. The statistics are now displayed at the bottom of the left panel

13819 - New option to retrieve batch name and parent batch name from Sample

In an assay run, on the Experimental Condition page, when using "Retrieve from Sample", a new option is available: Import batch name and parent batch name.

This option imports:

  • The batch name as the Sample Name
  • The parent batch name as the Sample Alias

13838 - Normalize plate by Well Type average

A new normalization Normalize plate by Well Type average is now available at the Well Validation step.

This normalization calculates: Readout / AVG(well_type) per plate

The normalization has 4 parameters:

  • Output name (mandatory): Choose the output name for the results
  • Readout (mandatory): Select which data to normalize
  • Well Type (mandatory): The well type to use for the Well Type average
  • Experimental Condition (optional): Apply this calculation to different groups in the same plate

13748 - New linear regression for multiple aggregations

A new "Back calculation" normalization has been added with new capabilities:

  • Reference Aggregation: The Reference Aggregation to apply the linear regression to
  • Output name: Choose a custom output name for the normalization results
  • Experimental Condition grouping: Apply the linear regression to different groups within the same plate by selecting an Experimental Condition

When the selected Reference Aggregation doesn't contain Plate Index or Well Type Name, these parameters are automatically added and the aggregation is recalculated.

13786 - Improved performance for Aggregation

Aggregation at the Sample Analysis Settings step and Reference Analysis Settings step has been improved.

Bugs resolved

13850 - Display text annotations

Fixed an issue where text annotations were not displayed in Assay. The t ext field now appears correctly when adding text annotations.

13936 - Run with Externally Loaded Data can now be copied

Fixed an issue preventing the copy of runs with externally loaded data.

13469 - Assay Designer Profile now has Access to Plate Layouts and Annotations

Fixed an issue where users with the Assay Designer profile could not access Plate Layouts and Annotations in Reference Data.

13595 - Dose Response Fitting at the Reference Analysis step

Fixed an issue where the Dose Response Fitting at the Reference Analysis step could not be compiled.


Warehouse

New Features

13570 - Categorize Warehouse Parameters

Warehouse parameters can now be categorized to distinguish between parameters that describe results and those that define analysis context.

  • Create and manage parameter categories in the Administration Panel > Parameter Categories page
  • Assign an optional category when creating or updating parameters
  • View parameter categories when editing protocols (available as an optional column)
  • When adding a parameter to a protocol, the selection list now displays category, type, and unit information for easier identification

Bugs resolved

13788 - Sample Barcode and Dose Unit Parameters Now Published Correctly

Fixed an issue where Sample Barcode and Dose Unit parameters were null when publishing runs to Warehouse.


Known bugs

General

#12720 Lists of values break some functionalities when the source vocabulary is too big. → Annotations (Assay), Assay Templates (Assay Catalog)

Sample

#13249 "Move & Dispose" Workflow - Invalid items are not ignored in the job

#12707 Impossible to cancel Edit Sourcing page when the selection is empty

#12582 Numbers are not displayed in dose layouts at the requesting step of the Plate Serial Dilution workflow

#12525 Inconsistent behavior of the batch list and the refresh icons in the Plate Creation workflow

#12416 A large amount of vocabulary items (~500+) can break the annotation edition at the task requesting step of the workflow "Container - Bulk Update Annotations Values"

#12360 During a reformatting job, if you select "Source" dilution with multiple copies, the dilution is listed multiple times in the generated worklist

#13455 Empty container creation workflow stuck when failed at first computation

#13457 Rack Storage Optimization workflow keeping previously loaded vials

#13524 Alternate sourcing is not properly displayed when going back to sourcing step

#13523 Not possible to delete/revert Rack Storage Optimization job when having an error

#13526 Can't revert a job when having an error at the Processing step

Assay

#12703 Endpoint final_results doesn't work when too many lines are returned

#12536 Wrong redirection to the homepage when a reader runs into an error

#13462 The format of the exports of Hits in Sample analysis is not correct when using multiple aggregations

#13442 Publishing bug if analysis contains an ECD parameter with a decimal value

#13461 Filters are not properly working if report is not fully loaded in Assay home page

#13493 Invalidated Warehouse protocols causing display issues in Assay

Assay Catalog

#12877 Assay descriptions cannot contain more than 4000 characters

#12502 The task title is not updated when the assay name is changed after requesting publication